Precursor to metabolite: Ramipril to Ramiprilat

Ramipril is converted to Ramiprilat by esterase.

Ramipril mascot — mnemonic cartoon — Ramipril — mascot

The pair

Ramipril — A widely used ACE inhibitor with strong cardiovascular outcome data.
Ramiprilat — Active ACE-inhibiting metabolite of ramipril; prolonged ACE binding sustains effects, while renal impairment increases exposure.

Ramipril · Ramiprilat · Open Ramipril in the interactive console ↗