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Ramiprilat

from ramipril

What it isThe active diacid metabolite of ramipril.

Why it mattersIt carries the outcome data: the cardiovascular protection attributed to ramipril in trials is pharmacologically ramiprilat’s.

What it changesLong tissue-ACE binding gives the sustained once-daily effect; renal impairment prolongs it further.

NO BOXED WARNINGS

Classes and tags

Clinical profile

Direct muscarinic antagonism0 / 4

Mechanism of action: Ramiprilat ballicule

Ramiprilat ballicule: receptor binding, kinetics and half-life diagram

Open Ramiprilat in the interactive console ↗