Precursor to metabolite: Morphine to Morphine-6glucuronide

Morphine is converted to Morphine-6glucuronide by UGT2B7.

Morphine mascot — mnemonic cartoon — Morphine — mascot

The pair

Morphine — The prototypical opioid analgesic and comparison standard.
Morphine-6glucuronide — Potent opioid-active morphine metabolite; renal accumulation can prolong analgesia, sedation, and respiratory depression.

Morphine · Morphine-6glucuronide · Open Morphine in the interactive console ↗