Precursor to metabolite: Latanoprost to Latanoprost free acid

Latanoprost is converted to Latanoprost free acid by corneal esterase.

Latanoprost mascot — mnemonic cartoon — Latanoprost — mascot

The pair

Latanoprost — First-line glaucoma drop; FP prostanoid prodrug that increases uveoscleral outflow.
Latanoprost free acid — Active latanoprost metabolite; prostaglandin FP-receptor activation increases uveoscleral outflow and lowers intraocular pressure.

Latanoprost · Latanoprost free acid · Open Latanoprost in the interactive console ↗