Precursor to metabolite: Codeine to Morphine
Codeine is converted to Morphine by CYP2D6.
The pair
- Codeine — Weak opioid and prodrug; CYP2D6 variability makes response unpredictable.
- Morphine — Prototypical opioid analgesic and comparison standard.
Anything that inhibits or induces CYP2D6 shifts the balance between Codeine and Morphine.
Codeine · Morphine · Open Codeine in the interactive console ↗