Precursor to metabolite: Cariprazine to Desmethylcariprazine
Cariprazine is converted to Desmethylcariprazine by CYP3A4.
The pair
- Cariprazine — D3-preferring dopamine partial agonist for schizophrenia, bipolar disorder, and adjunctive depression.
- Desmethylcariprazine — Cariprazine metabolite with the same D3-preferring partial agonism as the parent.
Anything that inhibits or induces CYP3A4 shifts the balance between Cariprazine and Desmethylcariprazine.
Cariprazine · Desmethylcariprazine · Open Cariprazine in the interactive console ↗