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Mechanisms
› Osmotic laxative
Osmotic laxative
Draws water into the bowel lumen — laxation
Drugs with this mechanism (4)
Lactulose
— Non-absorbed disaccharide; osmotic laxative that also traps ammonia in the colon.
Mg hydroxide
— OTC osmotic laxative and antacid (milk of magnesia).
PEG 3350/ electrolytes
— PEG-electrolyte bowel preparation; effective with little net fluid or electrolyte shift.
PEG 3350
— Well-tolerated OTC osmotic laxative for chronic constipation and bowel preparation.
All mechanisms
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