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PEG 3350/ electrolytes

GOLYTELY

What it isNonabsorbed osmotic laxative balanced with electrolytes; colonoscopy bowel preparation.

Why this oneThe balanced solution permits complete lavage with little net electrolyte movement, useful in renal or cardiac disease.

What limits itLarge volume and salty taste impair completion; nausea, bloating and aspiration are practical hazards.

FDA label

FDA dosingPopulationStartTargetMax
Colon cleansing before colonoscopy/barium enemaadults8 oz every 10 minutesuntil 4 liters consumed or rectal effluent is clear4 liters

Renal Use with caution (risk of renal injury); ensure hydration and consider baseline/post-procedure labs.

Hepatic Undefined

Do not take other laxatives concurrently.

Instructions

Contraindications

Cautions

Adverse reactions

Pregnancy No animal reproduction studies; use only if clearly needed.

Lactation Undefined

NO BOXED WARNINGS

Classes and tags

Clinical profile

Direct muscarinic antagonism0 / 4

Mechanism of action: PEG 3350/ electrolytes ballicule

PEG 3350/ electrolytes ballicule: receptor binding, kinetics and half-life diagram

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