NK1 antagonist
Neurokinin-1 receptor antagonist
- Prevents delayed chemotherapy-induced nausea and vomiting
Drugs with this mechanism (4)
- Aprepitant — NK1 antagonist antiemetic for delayed chemotherapy nausea.
- Elinzanetant — Dual NK1/NK3 (neurokinin) antagonist; hormone-free relief for menopausal hot flashes.
- Netupitant — Long-acting NK1 antagonist, given as a fixed pair with palonosetron.
- Rolapitant — Long-acting NK1 antiemetic for chemotherapy.
All mechanisms · Open the interactive console ↗