Mucosal stimulant

Colonic mucosal stimulant

Directly stimulates colonic mucosa and enteric nerves → ↑ motility and secretion
Reliable stimulant laxative effect
Cramping is mechanism-linked

Drugs with this mechanism (2)

Bisacodyl — OTC stimulant laxative.
Senna — OTC stimulant laxative from a plant.

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