Mucosal stimulant
Colonic mucosal stimulant
Mucosal stimulant — mechanism card
- Stimulates enteric nerves → ↑ motility and secretion
- Directly stimulates the colonic mucosa
- Reliable stimulant laxative effect
- Cramping
Drugs with this mechanism (2)
- Bisacodyl — OTC stimulant laxative.
- Senna — OTC stimulant laxative from a plant.
Self-check
- How does enteric-nerve stimulation affect the bowel?
Increases motility and secretion. - Which adverse effect is linked to mucosal-stimulant laxatives?
Cramping.
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