Glutathione repletion
- ➔ effectiveness falls sharply the longer treatment is delayed
- Also acts as a mucolytic by cleaving disulfide bonds in mucus
- ➔ ⚑ a separate mechanism from glutathione repletion
Drugs with this mechanism (2)
- Acetylcysteine — Glutathione precursor and mucolytic; the antidote for acetaminophen poisoning.
- N-acetylcysteine (NAC) — Glutathione precursor; the antidote for acetaminophen overdose, also a mucolytic.
All mechanisms · Open the interactive console ↗