L-type CCB

Name: L-type CCB
Creator: Jason Cafer, MD

L-type calcium channel blocker

Drugs with this mechanism (15)

Amlodipine — Long-acting dihydropyridine CCB for hypertension and angina; ankle edema often limits it.
Clevidipine — Ultra-short IV dihydropyridine for acute blood-pressure control.
Diltiazem — Non-dihydropyridine CCB for rate control and blood pressure.
Diltiazem ER — Extended-release non-DHP CCB for hypertension/angina; bradycardia and CYP3A4 interactions.
Etripamil — Self-administered nasal L-type calcium-channel blocker for terminating paroxysmal SVT.
Felodipine — Dihydropyridine CCB antihypertensive; grapefruit interaction.
Isradipine — Shorter-acting dihydropyridine CCB for hypertension; edema and reflex tachycardia limit use.
Lavender — Lavender oil (silexan); a mild anxiolytic supplement.
Nicardipine — IV/oral dihydropyridine CCB for acute hypertension.
Nifedipine — Prototypical dihydropyridine CCB; avoid immediate-release use for rapid blood-pressure lowering.
Nifedipine ER (GITS) — Long-acting dihydropyridine calcium-channel blocker; edema is the common limit.
Nimodipine — Oral dihydropyridine CCB that improves neurologic outcome after aneurysmal subarachnoid hemorrhage.
Nisoldipine — Food-sensitive dihydropyridine CCB for hypertension; largely displaced by amlodipine.
Verapamil — Non-dihydropyridine CCB for rate control; constipation, negative inotropy.
Verapamil ER — Extended-release non-dihydropyridine calcium-channel blocker for hypertension and rate control.