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Verapamil ER

CALAN SR

What it isL-type calcium-channel blocker that slows AV conduction and relaxes arteries; hypertension, angina, and supraventricular arrhythmias.

Why this oneIts strong AV-nodal effect provides rate control that dihydropyridine calcium-channel blockers cannot.

What limits itConstipation, bradycardia, and heart block limit use; avoid systolic heart failure and watch CYP3A4 and P-gp interactions.

NO BOXED WARNINGS

Classes and tags

Clinical profile

Direct muscarinic antagonism0 / 4

Mechanism of action: Verapamil ER ballicule

Verapamil ER ballicule: receptor binding, kinetics and half-life diagram

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