Bupropion SR (smoking cessation)
ZYBAN
What it isNorepinephrine-dopamine reuptake inhibitor and neuronal nicotinic antagonist; smoking cessation.
Why this oneUnder ZYBAN, the smoking-cessation indication lives here, not on Wellbutrin; same 150 mg SR tablet, but this label is for quitting.
What limits itDose-related seizures rule it out in seizure or eating disorders; insomnia, hypertension, and the suicidality warning also matter.
FDA-approved for
- smoking cessation (1997)
⚠ BOXED WARNING
- Suicidal thoughts and behaviors in patients under 25
Classes and tags
Clinical profile
Active metabolites
Mechanism of action: Bupropion SR (smoking cessation) ballicule
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Memory aids: mascots and interaction avatars
Strong CYP2D6 inHibitor
Skinny → weight loss possible
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