Sumatriptan nasal
IMITREX
What it isNasal 5-HT1B/1D agonist (IMITREX 5-20 mg, 1997); abortive treatment of acute migraine.
Why this oneNeedle-free TOSYMRA 10 mg spray and ONZETRA XSAIL 11 mg powder bypass swallowing and gastric delay; faster than oral, slower than subcutaneous.
What limits itCoronary vasospasm precludes use in ischemic or vasospastic disease; overuse can perpetuate headache.
FDA-approved for
- acute migraine (1997)
NO BOXED WARNINGS
Principal riskCoronary vasospasm; contraindicated in ischemic heart disease
Classes and tags
Clinical profile
Mechanism of action: Sumatriptan nasal ballicule
Open Sumatriptan nasal in the interactive console ↗
Memory aids: mascots and interaction avatars
