Sumatriptan SC injection
IMITREX
What it isSubcutaneous 5-HT1B/1D agonist (IMITREX, 1992) causing cranial vasoconstriction; acute migraine and cluster headache.
Why this oneThe injection is the fastest triptan route, with relief possible within 10 minutes, and the only sumatriptan form also labeled for acute cluster headache.
What limits itCoronary vasospasm and chest symptoms preclude use in ischemic vascular disease; do not combine with ergot drugs.
FDA-approved for
- acute migraine (1992)
- acute cluster headache (1992)
NO BOXED WARNINGS
Principal riskCoronary vasospasm; contraindicated in ischemic heart disease
Classes and tags
Clinical profile
Mechanism of action: Sumatriptan SC injection ballicule
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