Serdexmethylphenidate
in AZSTARYS
What it isInactive prodrug of dexmethylphenidate — 70% of AZSTARYS (2021), cleaved in the lower GI tract for a smoother, extended d-MPH curve.
Why this oneThe prodrug IS the delivery system: no drug until enzymatic conversion, which blunts abuse by insufflation or injection.
What limits itNo pharmacology of its own — the card points down the arrow to dexmethylphenidate.
FDA-approved for
- ADHD (in AZSTARYS) (2021)
⚠ BOXED WARNING
- Abuse, misuse and addiction
Classes and tags
Clinical profile
Active metabolites
Mechanism of action: Serdexmethylphenidate ballicule
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