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Mesalamine DR

LIALDA

What it isPPAR-gamma agonist and 5-lipoxygenase inhibitor acting locally in bowel; ulcerative colitis induction and maintenance.

Why this oneIts multimatrix delayed release spreads mesalamine through the colon, and products are not freely interchangeable.

What limits itCheck renal function for interstitial nephritis; paradoxical acute intolerance causes worse pain, diarrhea, and bleeding.

NO BOXED WARNINGS

Classes and tags

Clinical profile

Direct muscarinic antagonism0 / 4

Mechanism of action: Mesalamine DR ballicule

Mesalamine DR ballicule: receptor binding, kinetics and half-life diagram

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