Lorazepam injection
ATIVAN INJECTION
What it isInjectable GABA-A positive modulator; status epilepticus and preanesthetic sedation.
Why this oneFor inpatient agitation it offers reliable IM absorption, no active metabolites, and conjugation-only metabolism.
What limits itRespiratory depression, especially stacked with opioids or in pulmonary disease; propylene glycol load with prolonged infusions.
FDA-approved for
- status epilepticus (~1980)
- preanesthetic sedation (~1980)
⚠ BOXED WARNINGS
- Risk from concomitant use with opioids
- Abuse, misuse and addiction
- Dependence and withdrawal reactions
Classes and tags
Clinical profile
Mechanism of action: Lorazepam injection ballicule
