Desogestrel
in DESOGEN
What it isThird-generation progestin used in combined and progestin-only pills.
Why this oneLow androgenicity, and the progestin-only pill has a twelve-hour window rather than three.
What limits itA higher VTE risk than levonorgestrel-containing combined pills. Irregular bleeding.
FDA-approved for
- contraception with ethinyl estradiol
⚠ BOXED WARNING
- Cigarette smoking and serious cardiovascular events over age 35
Cost, est. cash$300–$2,500/month
Generic entry1999
Classes and tags
Clinical profile
Legacy pregnancy categoryX
Defining liabilityVenous thromboembolism and hormone-related adverse effects; estrogen also lowers lamotrigine exposure.
Mechanism of action: Desogestrel ballicule
Open Desogestrel in the interactive console ↗
Memory aids: mascots and interaction avatars
