Choline
What it isEssential nutrient; acetylcholine precursor.
Why this oneSupply can limit acetylcholine synthesis, which is the rationale behind choline-donor supplements.
What limits itSupplement evidence for cognition is weak; the rate-limiting step is usually the transporter, not substrate supply.
NO BOXED WARNINGS
Principal riskEndogenous or dietary; no boxed warning applies
Classes and tags
Available strengths
- tab 250, 500 mg (bitartrate)
Active metabolites
Open Choline in the interactive console ↗
Self-check
- How strong is evidence for choline supplements improving cognition?
Weak. - What usually limits acetylcholine synthesis rather than choline supply?
The transporter.