Acetylcholine
MIOCHOL
What it isNeurotransmitter at muscarinic and nicotinic receptors throughout the autonomic and somatic systems.
Why it mattersAlmost every cholinergic drug mimics, blocks or preserves it.
What it changesRapid acetylcholinesterase hydrolysis makes cholinesterase inhibitors, not receptor agonists, the practical way to raise cholinergic tone.
NO BOXED WARNINGS
Principal riskEndogenous or dietary; no boxed warning applies
Classes and tags
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Self-check
- Which enzyme rapidly hydrolyzes acetylcholine?
Acetylcholinesterase. - Which two receptor families respond to acetylcholine?
Muscarinic and nicotinic.