Librax
Combination product
Pronunciation: klor-dye-az-e-POX-ide and kli-DIN-ee-um
What it isChlordiazepoxide 5 mg plus clidinium bromide 2.5 mg per capsule (LIBRAX): for the emotional and somatic factors in GI disorders, and as an adjunct in peptic ulcer, irritable bowel syndrome and acute enterocolitis.
Why this oneA benzodiazepine for the anxiety component and a quaternary antimuscarinic for spasm and secretion in one capsule; 1–2 capsules 3–4 times daily before meals and at bedtime.
What limits itCarries the benzodiazepine boxed warning (opioid co-use; abuse, misuse and addiction; dependence and withdrawal). Anticholinergic effects; contraindicated in glaucoma and prostatic hypertrophy. Older adults start at no more than 2 capsules a day.
Components (2)
FDA-approved for
- emotional and somatic factors in GI disorders (1966)
- adjunct: peptic ulcer, irritable bowel syndrome, acute enterocolitis (1966)