UGT inducer

Induces UGT/glucuronidation pathways
Substrate clearance can increase
Exposure/efficacy may fall
Onset and offset take time
Some inducers also induce CYP enzymes

Interaction at a glance

Induces UGT/glucuronidation pathways

Magnitude / time course

Induces UGT/glucuronidation pathways
Substrate clearance can increase

Mechanism

Onset and offset take time
Some inducers also induce CYP enzymes

Exposure modifiers

Exposure/efficacy may fall

Self-check

What does “UGT inducer” mean?
Induces UGT/glucuronidation pathways.

Drugs in this interaction (10)

Estradiol ballicule — decagon mechanism diagram — Estradiol

Ritonavir ballicule — decagon mechanism diagram — Ritonavir

Carbamazepine ballicule — decagon mechanism diagram — Carbamazepine

Primidone ballicule — decagon mechanism diagram — Primidone

Phenytoin ballicule — decagon mechanism diagram — Phenytoin

Conjugated estrogens ballicule — decagon mechanism diagram — Conjugated estrogens

Phenobarbital ballicule — decagon mechanism diagram — Phenobarbital

Rifampin ballicule — decagon mechanism diagram — Rifampin

Ethinyl estradiol ballicule — decagon mechanism diagram — Ethinyl estradiol

St John's wort ballicule — decagon mechanism diagram — St John's wort

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