UGT inducer
- Induces UGT/glucuronidation pathways
- Substrate clearance can increase
- Exposure/efficacy may fall
- Onset and offset take time
- Some inducers also induce CYP enzymes
Interaction at a glance
- Induces UGT/glucuronidation pathways
Magnitude / time course
- Induces UGT/glucuronidation pathways
- Substrate clearance can increase
Mechanism
- Onset and offset take time
- Some inducers also induce CYP enzymes
Exposure modifiers
- Exposure/efficacy may fall
Self-check
- Can UGT inducers also induce CYP enzymes?
Yes; some do. - How can UGT induction affect substrate clearance?
Increase it.
Drugs in this interaction (10)
All interaction examples · Open UGT inducer in the interactive console ↗