Prostaglandin analogs (ophthalmic)
- First-line ocular-pressure lowering drugs
- Increase uveoscleral outflow
- Latanoprost/bimatoprost/travoprost common
- Once-daily dosing + strong efficacy
- Iris pigmentation + eyelash growth
- Periocular fat atrophy can alter appearance
- Minimal systemic cardiovascular effects
Class at a glance
- First-line ocular-pressure lowering drugs
Practical pearls
- Increase uveoscleral outflow
Members / distinctions
- Latanoprost/bimatoprost/travoprost common
- Once-daily dosing + strong efficacy
Other member distinctions
- Iris pigmentation + eyelash growth
- Periocular fat atrophy can alter appearance
- Minimal systemic cardiovascular effects
Self-check
- Which drug class is first-line for ocular-pressure lowering?
Prostaglandin analogs (ophthalmic). - What outflow pathway do ophthalmic prostaglandin analogs increase?
Uveoscleral outflow.
Drugs in this class (3)
Prostaglandin analogs (ophthalmic) prescription history
Animated chart of estimated U.S. prescriptions per year, Glaucoma medicines (1900–2026). Prostaglandins highlighted from 1996.
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