Immunosuppressants (mTOR inhibitors)
- Sirolimus/everolimus inhibit mTOR
- Suppress lymphocyte proliferation
- Used in transplantation + selected cancers
- Hyperlipidemia + cytopenias are common
- Impair wound healing
- CYP3A/P-gp interactions are important
Class at a glance
- Sirolimus/everolimus inhibit mTOR
Pharmacology
- CYP3A/P-gp interactions are important
Clinical role
- Suppress lymphocyte proliferation
- Used in transplantation + selected cancers
Members / distinctions
- Hyperlipidemia + cytopenias are common
- Impair wound healing
Self-check
- What is the main pharmacologic action of Immunosuppressants (mTOR inhibitors)?
Sirolimus/everolimus inhibit mTOR.
Drugs in this class (3)
All drug classes · Open the interactive console ↗
