H1 antihistamines (second-generation)
- Less CNS penetration than first-gen H1 drugs
- Cetirizine/loratadine/fexofenadine examples
- Preferred for chronic rhinitis/urticaria
- Much less antimuscarinic burden
- Cetirizine can still cause some sedation
- Once-daily dosing is common
Class at a glance
- Less CNS penetration than first-gen H1 drugs
Members / distinctions
- Cetirizine/loratadine/fexofenadine examples
- Much less antimuscarinic burden
Other member distinctions
- Preferred for chronic rhinitis/urticaria
- Once-daily dosing is common
Safety / monitoring
- Cetirizine can still cause some sedation
Drugs in this class (7)
All drug classes · Open the interactive console ↗
