Endogenous neurotransmitters (opioid peptides)
- Endogenous ligands for opioid receptors
- Endorphins, enkephalins + dynorphins
- Modulate pain, stress, reward + respiration
- Peptides are rapidly degraded
- Receptor selectivity differs by peptide
- Not pharmacokinetically equivalent to opioid drugs
Class at a glance
- Endogenous ligands for opioid receptors
Pharmacology
- Receptor selectivity differs by peptide
Clinical role
- Endorphins, enkephalins + dynorphins
- Modulate pain, stress, reward + respiration
Practical pearls
- Peptides are rapidly degraded
- Not pharmacokinetically equivalent to opioid drugs
Drugs in this class (5)
All drug classes · Open the interactive console ↗
