Antipsychotics (second-generation / SGAs)

Class at a glance

• Mainstay antipsychotics; profiles vary widely

Safety / monitoring

• Schizophrenia + bipolar; some adjunct MDD
• clozapine: TRS + suicide-risk reduction
• aripiprazole-like: less prolactin burden

Clinical role

• LAIs help when preferred/adherence is poor
• Do not treat “SGA” as one AE profile

Safety distinctions

• Metabolic, EPS + prolactin risks vary

Drugs in this class (17)

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