Antipsychotics (first-generation / FGAs)

Class at a glance

• Potent D2-blocking antipsychotics

Practical pearls

• High-potency → more EPS/prolactin
• haloperidol, fluphenazine

Clinical role

• Schizophrenia; agitation; some antiemetic use

Safety / monitoring

• Low-potency → sedation/orthostasis
• chlorpromazine
• TD/NMS risk; often less metabolic burden

Drugs in this class (14)

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