Anticoagulants (DOACs)
- Oral anticoagulants without routine INR
- AF stroke prevention + VTE treatment
- Apixaban/rivaroxaban/edoxaban inhibit Xa
- Dabigatran directly inhibits thrombin
- Fast onset; renal function matters
- Fewer food interactions than warfarin
- Major bleeding; adherence is crucial
- Avoid for mechanical heart valves
Class at a glance
- Oral anticoagulants without routine INR
Pharmacology
- Apixaban/rivaroxaban/edoxaban inhibit Xa
- Dabigatran directly inhibits thrombin
Clinical role
- AF stroke prevention + VTE treatment
- Fewer food interactions than warfarin
Safety / monitoring
- Fast onset; renal function matters
- Major bleeding; adherence is crucial
- Avoid for mechanical heart valves
Drugs in this class (4)
All drug classes · Open the interactive console ↗
