Ulcerative colitis (UC)
- Mild distal disease → mesalamine first
- More extensive mild disease → oral + rectal 5-ASA
- Steroid only for induction of active flares
- Moderate–severe → advanced biologic/small molecule
- Maintain steroid-free remission
- Acute severe UC → IV steroid, then rescue therapy
- Colectomy is curative for colitis
Use at a glance
- Mild distal disease → mesalamine first
Treatment options
- Steroid only for induction of active flares
- Maintain steroid-free remission
Other treatment options
- Acute severe UC → IV steroid, then rescue therapy
- Colectomy is curative for colitis
Practical pearls
- More extensive mild disease → oral + rectal 5-ASA
- Moderate–severe → advanced biologic/small molecule
Self-check
- What is recommended for Moderate–severe in Ulcerative colitis (UC)?
advanced biologic/small molecule.
Drugs used for this (11)
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