Systemic lupus erythematosus (SLE)
- Hydroxychloroquine for most patients
- Minimize chronic glucocorticoid exposure
- Add immunosuppressant by organ/severity
- Belimumab/anifrolumab for selected active disease
- Lupus nephritis needs kidney-specific regimen
- Control CV, bone, infection + pregnancy risks
- Treatment aims for remission/low disease activity
Use at a glance
- Hydroxychloroquine for most patients
Treatment options
- Minimize chronic glucocorticoid exposure
- Add immunosuppressant by organ/severity
- Lupus nephritis needs kidney-specific regimen
- Treatment aims for remission/low disease activity
Choosing treatment
- Belimumab/anifrolumab for selected active disease
Practical pearls
- Control CV, bone, infection + pregnancy risks
Self-check
- Which drug is used for most SLE patients?
Hydroxychloroquine. - What is the treatment target in SLE?
Remission or low disease activity.
Drugs used for this (3)
All clinical uses · Open Systemic lupus erythematosus (SLE) in the interactive console ↗