Syndrome of inappropriate antidiuretic hormone secretion (SIADH)
- Treat cause + stop contributing drugs
- Fluid restriction is common first-line chronic therapy
- Severe symptoms → hypertonic saline
- Urea or loop/solute strategies can help
- Vaptan is selective and requires careful monitoring
- Avoid overly rapid sodium correction
Use at a glance
- Treat cause + stop contributing drugs
Treatment options
- Fluid restriction is common first-line chronic therapy
Practical pearls
- Urea or loop/solute strategies can help
Other practical pearls
- Severe symptoms → hypertonic saline
Monitoring / follow-up
- Vaptan is selective and requires careful monitoring
- Avoid overly rapid sodium correction
Self-check
- What should be treated or removed in SIADH?
The cause and contributing drugs.
- What should be avoided during SIADH correction?
Overly rapid sodium correction.
Drugs used for this (2)
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