Resistant hypertension
- Confirm adherence + out-of-office BP first
- Exclude secondary causes and interfering drugs
- Optimize ACEi/ARB + long-acting CCB + thiazide-like diuretic
- Spironolactone is preferred fourth-line for many
- Check K+, kidney function + sodium intake
- Device therapies remain specialist options
Use at a glance
- Confirm adherence + out-of-office BP first
Treatment options
- Exclude secondary causes and interfering drugs
- Optimize ACEi/ARB + long-acting CCB + thiazide-like diuretic
Practical pearls
- Spironolactone is preferred fourth-line for many
- Device therapies remain specialist options
Other practical pearls
- Check K+, kidney function + sodium intake
Self-check
- What is checked in resistant hypertension?
K+, kidney function + sodium intake. - What is excluded in resistant hypertension?
Secondary causes and interfering drugs.
Drugs used for this (8)
All clinical uses · Open Resistant hypertension in the interactive console ↗