Pregnancy-associated nausea/vomiting
- Pyridoxine ± doxylamine is first-line
- Add antihistamine/dopamine antagonist/ondansetron as needed
- Hydrate + replace thiamine before dextrose in prolonged vomiting
- Hyperemesis may require IV therapy/nutrition support
- Exclude thyroid, GI, neurologic + molar causes when severe
- Balance fetal data against maternal dehydration/malnutrition
Use at a glance
- Pyridoxine ± doxylamine is first-line
Practical pearls
- Add antihistamine/dopamine antagonist/ondansetron as needed
- Balance fetal data against maternal dehydration/malnutrition
Choosing treatment
- Exclude thyroid, GI, neurologic + molar causes when severe
Treatment options
- Hydrate + replace thiamine before dextrose in prolonged vomiting
- Hyperemesis may require IV therapy/nutrition support
Self-check
- What is first-line medication treatment for pregnancy-associated nausea/vomiting?
Pyridoxine ± doxylamine.
- What should precede dextrose in prolonged vomiting?
Thiamine replacement.
Drugs used for this (2)
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