Postoperative nausea/vomiting (PONV)
- Assess baseline PONV risk
- Reduce emetogenic anesthesia/opioids when possible
- Moderate/high risk → multimodal prophylaxis
- dexamethasone + 5-HT3 commonly paired
- Rescue with a different drug class
- Droperidol/amisulpride are useful alternatives
- Hydration + opioid-sparing also help
Use at a glance
- Assess baseline PONV risk
Practical pearls
- Droperidol/amisulpride are useful alternatives
- Hydration + opioid-sparing also help
Choosing treatment
- Reduce emetogenic anesthesia/opioids when possible
- Rescue with a different drug class
Other practical pearls
- Moderate/high risk → multimodal prophylaxis
- dexamethasone + 5-HT3 commonly paired
Self-check
- What prophylaxis suits moderate/high PONV risk?
Multimodal prophylaxis. - What measures besides antiemetics help prevent PONV?
Hydration + opioid-sparing.
Drugs used for this (6)
All clinical uses · Open Postoperative nausea/vomiting (PONV) in the interactive console ↗