Parkinson disease psychosis
- Remove nonessential psychosis-provoking drugs first
- Reduce PD drugs cautiously if motor function allows
- Pimavanserin is FDA-approved
- Clozapine is effective but needs ANC monitoring
- Quetiapine is common despite weaker evidence
- Avoid potent D2 blockers that worsen parkinsonism
- Check delirium/infection before labeling PD psychosis
Use at a glance
- Remove nonessential psychosis-provoking drugs first
Practical pearls
- Pimavanserin is FDA-approved
- Quetiapine is common despite weaker evidence
Choosing treatment
- Reduce PD drugs cautiously if motor function allows
Monitoring / follow-up
- Clozapine is effective but needs ANC monitoring
- Avoid potent D2 blockers that worsen parkinsonism
- Check delirium/infection before labeling PD psychosis
Self-check
- What should be checked in Parkinson disease psychosis?
delirium/infection before labeling PD psychosis.
- What should generally be avoided in Parkinson disease psychosis?
potent D2 blockers that worsen parkinsonism.
Drugs used for this (1)
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