Parkinson disease — motor symptoms
- Levodopa gives the greatest motor benefit
- Use when symptoms impair quality/function
- Dopamine agonist may suit selected younger pts
- MAO-B inhibitor gives modest early benefit
- Titrate to function—not a preset dose target
- Hallucination/orthostasis rise with dopaminergics
- Exercise/physical therapy are core treatment
Use at a glance
- Levodopa gives the greatest motor benefit
Practical pearls
- MAO-B inhibitor gives modest early benefit
Treatment options
- Titrate to function—not a preset dose target
- Exercise/physical therapy are core treatment
Choosing treatment
- Use when symptoms impair quality/function
- Dopamine agonist may suit selected younger pts
- Hallucination/orthostasis rise with dopaminergics
Self-check
- Which drug gives the greatest motor benefit in Parkinson disease?
Levodopa. - What guides Parkinson motor-treatment titration?
Function.
Drugs used for this (12)
All clinical uses · Open Parkinson disease — motor symptoms in the interactive console ↗