Opioid withdrawal
- Buprenorphine or methadone is preferred
- Treat withdrawal as entry to ongoing OUD treatment
- Lofexidine/clonidine reduce adrenergic symptoms
- Add symptom-specific antiemetic/antidiarrheal care
- Avoid precipitated withdrawal when starting buprenorphine
- Detox alone has high relapse/overdose risk
Use at a glance
- Buprenorphine or methadone is preferred
Treatment options
- Treat withdrawal as entry to ongoing OUD treatment
Practical pearls
- Lofexidine/clonidine reduce adrenergic symptoms
- Add symptom-specific antiemetic/antidiarrheal care
Safety / pitfalls
- Avoid precipitated withdrawal when starting buprenorphine
- Detox alone has high relapse/overdose risk
Self-check
- What should be treated in Opioid withdrawal?
withdrawal as entry to ongoing OUD treatment.
- What should generally be avoided in Opioid withdrawal?
precipitated withdrawal when starting.
Drugs used for this (1)
All clinical uses · Open the interactive console ↗