Opioid withdrawal
- Buprenorphine or methadone is preferred
- Treat withdrawal as entry to ongoing OUD treatment
- Lofexidine/clonidine reduce adrenergic symptoms
- Add symptom-specific antiemetic/antidiarrheal care
- Avoid precipitated withdrawal when starting buprenorphine
- Detox alone has high relapse/overdose risk
Use at a glance
- Buprenorphine or methadone is preferred
Treatment options
- Treat withdrawal as entry to ongoing OUD treatment
Practical pearls
- Lofexidine/clonidine reduce adrenergic symptoms
- Add symptom-specific antiemetic/antidiarrheal care
Safety / pitfalls
- Avoid precipitated withdrawal when starting buprenorphine
- Detox alone has high relapse/overdose risk
Self-check
- Why is detoxification alone insufficient for opioid withdrawal?
High relapse/overdose risk. - What should be avoided when starting buprenorphine for opioid withdrawal?
Precipitated withdrawal.
Drugs used for this (1)
All clinical uses · Open Opioid withdrawal in the interactive console ↗