Nephrogenic diabetes insipidus
- Remove reversible cause when possible
- Maintain free-water access
- Thiazide + low-solute diet reduces urine volume
- Amiloride is especially useful for lithium-induced disease
- NSAID can reduce urine output but adds renal risk
- Desmopressin is usually much less effective than in central DI
Use at a glance
- Remove reversible cause when possible
Practical pearls
- Maintain free-water access
- Thiazide + low-solute diet reduces urine volume
Other practical pearls
- Amiloride is especially useful for lithium-induced disease
- Desmopressin is usually much less effective than in central DI
Clinical pearls
- NSAID can reduce urine output but adds renal risk
Self-check
- What is recommended for Nephrogenic diabetes insipidus?
Remove reversible cause when possible.
Drugs used for this (2)
All clinical uses · Open the interactive console ↗
