Lambert-Eaton myasthenic syndrome (LEMS)
- Treat underlying cancer when present
- Amifampridine improves neuromuscular transmission
- Pyridostigmine can provide additional symptomatic benefit
- Immunotherapy for persistent autoimmune disease
- Screen for small-cell lung cancer
- Avoid drugs that worsen neuromuscular transmission
Use at a glance
- Treat underlying cancer when present
Practical pearls
- Amifampridine improves neuromuscular transmission
- Pyridostigmine can provide additional symptomatic benefit
Treatment options
- Immunotherapy for persistent autoimmune disease
- Screen for small-cell lung cancer
Safety / pitfalls
- Avoid drugs that worsen neuromuscular transmission
Self-check
- What should be treated in Lambert-Eaton myasthenic syndrome (LEMS)?
underlying cancer when present.
- What should generally be avoided in Lambert-Eaton myasthenic syndrome (LEMS)?
drugs that worsen neuromuscular transmission.
Drugs used for this (1)
All clinical uses · Open the interactive console ↗
