Hyponatremia (euvolemic/hypervolemic)
- Treat symptoms/severity before the cause is fully corrected
- Severe neurologic symptoms → hypertonic saline
- Chronic SIADH: fluid restriction is common first step
- Increase solute/loop or vaptan in selected cases
- Hypervolemic disease requires treating HF/cirrhosis/kidney cause
- Avoid overly rapid correction → osmotic demyelination
Use at a glance
- Treat symptoms/severity before the cause is fully corrected
Practical pearls
- Chronic SIADH: fluid restriction is common first step
- Hypervolemic disease requires treating HF/cirrhosis/kidney cause
Choosing treatment
- Severe neurologic symptoms → hypertonic saline
- Increase solute/loop or vaptan in selected cases
Safety / pitfalls
- Avoid overly rapid correction → osmotic demyelination
Self-check
- What should be treated in Hyponatremia (euvolemic/hypervolemic)?
symptoms/severity before the cause is fully corrected.
- What is a common first pharmacotherapy for Hyponatremia (euvolemic/hypervolemic)?
Chronic SIADH: fluid restriction.
Drugs used for this (2)
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