Hepatitis B virus (HBV) infection
- Treat active/high-risk chronic HBV
- Preferred nucleos(t)ides have high resistance barrier
- tenofovir or entecavir
- Therapy often suppresses rather than eradicates HBV
- Monitor ALT, HBV DNA + cirrhosis/HCC risk
- Do not abruptly stop without monitoring plan
- HIV coinfection requires HBV-active ART
Use at a glance
- Treat active/high-risk chronic HBV
Practical pearls
- Preferred nucleos(t)ides have high resistance barrier
- tenofovir or entecavir
Treatment options
- Therapy often suppresses rather than eradicates HBV
- HIV coinfection requires HBV-active ART
Monitoring / follow-up
- Monitor ALT, HBV DNA + cirrhosis/HCC risk
- Do not abruptly stop without monitoring plan
Self-check
- Does HBV therapy usually eradicate infection?
No—it often suppresses rather than eradicates. - What is monitored in HBV?
ALT, HBV DNA + cirrhosis/HCC risk.
Drugs used for this (3)
All clinical uses · Open Hepatitis B virus (HBV) infection in the interactive console ↗