Heart failure with preserved ejection fraction (HFpEF)
- Treat congestion + major comorbid drivers
- SGLT2 inhibitor = core disease-modifying drug
- Control BP, AF, ischemia, obesity + diabetes
- Diuretics for volume overload
- MRA/ARNI may help selected patients
- Finerenone now labeled for HF with EF ≥40%
Use at a glance
- Treat congestion + major comorbid drivers
Treatment options
- SGLT2 inhibitor = core disease-modifying drug
Practical pearls
- Control BP, AF, ischemia, obesity + diabetes
- Diuretics for volume overload
Choosing treatment
- MRA/ARNI may help selected patients
- Finerenone now labeled for HF with EF ≥40%
Self-check
- What treats HFpEF volume overload?
Diuretics. - What is the core disease-modifying drug class in HFpEF?
An SGLT2 inhibitor.
Drugs used for this (8)
All clinical uses · Open Heart failure with preserved ejection fraction (HFpEF) in the interactive console ↗