Gout
- Long-term goal: prevent flares/tophi
- Allopurinol = preferred urate-lowering drug
- Start low; titrate to serum urate <6 mg/dL
- Flare prophylaxis during initiation
- colchicine/NSAID/low-dose steroid
- Febuxostat if allopurinol unsuitable
- Lifestyle helps but rarely replaces ULT
Use at a glance
- Long-term goal: prevent flares/tophi
Treatment options
- Allopurinol = preferred urate-lowering drug
- Start low; titrate to serum urate <6 mg/dL
Other treatment options
- Flare prophylaxis during initiation
- colchicine/NSAID/low-dose steroid
- Lifestyle helps but rarely replaces ULT
Choosing treatment
- Febuxostat if allopurinol unsuitable
Self-check
- What should be started in Gout?
low; titrate to serum urate <6 mg/dL.
- What is the long-term treatment goal in Gout?
prevent flares/tophi.
Drugs used for this (4)
All clinical uses · Open the interactive console ↗
