Cryptococcosis
- CNS/severe disease needs induction combination therapy
- amphotericin B + flucytosine
- Then prolonged fluconazole consolidation/maintenance
- Measure/opening pressure in cryptococcal meningitis
- Repeated lumbar puncture may be lifesaving
- HIV timing of ART requires specialist coordination
Use at a glance
- CNS/severe disease needs induction combination therapy
- amphotericin B + flucytosine
Practical pearls
- Then prolonged fluconazole consolidation/maintenance
Other practical pearls
- Measure/opening pressure in cryptococcal meningitis
Clinical pearls
- Repeated lumbar puncture may be lifesaving
- HIV timing of ART requires specialist coordination
Self-check
- What is needed for CNS/severe disease in Cryptococcosis?
induction combination.
- What is required when HIV timing of ART occurs in Cryptococcosis?
specialist coordination.
Drugs used for this (2)
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