Chronic idiopathic constipation (CIC)
- Fiber if intake is low and no obstruction
- PEG is a strong first-line osmotic option
- Stimulant laxative for rescue/adjunct
- Persistent CIC → secretagogue or prucalopride
- Match drug to bloating/pain/diarrhea tolerance
- Evaluate alarm features + secondary causes
- Avoid chronic ineffective stool-softener monotherapy
Use at a glance
- Fiber if intake is low and no obstruction
Treatment options
- PEG is a strong first-line osmotic option
Other treatment options
- Stimulant laxative for rescue/adjunct
- Persistent CIC → secretagogue or prucalopride
- Match drug to bloating/pain/diarrhea tolerance
- Evaluate alarm features + secondary causes
Safety / pitfalls
- Avoid chronic ineffective stool-softener monotherapy
Self-check
- What tolerability issues guide CIC drug choice?
Bloating/pain/diarrhea tolerance. - Which ineffective CIC monotherapy should not continue chronically?
Chronic ineffective stool-softener monotherapy.
Drugs used for this (4)
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