Chemotherapy-induced anemia
- Exclude bleeding, iron/B12/folate + hemolysis first
- Transfusion gives fastest correction when symptomatic/severe
- ESA only in selected noncurative chemotherapy settings
- ESA raises thrombosis risk and targets modest Hb
- Correct iron deficiency to improve response
- Avoid ESA when cure is the treatment intent unless indicated
Use at a glance
- Exclude bleeding, iron/B12/folate + hemolysis first
Choosing treatment
- ESA only in selected noncurative chemotherapy settings
- Correct iron deficiency to improve response
Treatment selection
- Transfusion gives fastest correction when symptomatic/severe
Safety / pitfalls
- ESA raises thrombosis risk and targets modest Hb
- Avoid ESA when cure is the treatment intent unless indicated
Self-check
- What alternative causes are excluded in chemotherapy anemia?
Bleeding, iron/B12/folate + hemolysis first.
- When should ESA be avoided unless indicated?
When cure is the chemotherapy intent.
Drugs used for this (2)
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