Bipolar disorder (depression)
- Avoid antidepressant monotherapy
- Quetiapine is a major first-line option
- Lurasidone/cariprazine/lumateperone useful
- Lithium/lamotrigine also evidence-based
- Choose by polarity, prior response + AEs
- Antidepressant only selectively + mood stabilizer
Use at a glance
- Avoid antidepressant monotherapy
Treatment options
- Quetiapine is a major first-line option
Practical pearls
- Lurasidone/cariprazine/lumateperone useful
- Lithium/lamotrigine also evidence-based
Other practical pearls
- Choose by polarity, prior response + AEs
- Antidepressant only selectively + mood stabilizer
Self-check
- What should generally be avoided in Bipolar disorder (depression)?
antidepressant monotherapy.
- What factors should guide treatment choice for Bipolar disorder (depression)?
polarity, prior response + AEs.
Drugs used for this (4)
All clinical uses · Open the interactive console ↗
